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pentobarbital will decrease the extent or impact of pimozide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.pentobarbital will minimize the level or influence of darifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital raises toxicity of methoxyflura